Transcriptome analysis of Didymella segeticola cultured on PDB medium and PDB-ferimzone mixed medium

Didymella segeticola (Basionym: Phoma segeticola) is a pathogenic that causes leaf spot on tea plant (Camellia sinensis), and causes decline in both tea leaves' quality and production accordingly. Tea plant have been widely grown in Guizhou province, China and the cultivation area in the region ranks first among all the province or cities in China. The leaf spot disease causes by Didymella segeticola was first identified in Shiqian County, Guizhou province, and later confirmed by our research group. Ferimzone is a hydrazone fungicide originally developed by Japan's Takeda Pharmaceutical Company Limited. By analysis the transcriptomic differences between Didymella segeticola cultured in PDB medium and PDB-ferimzone mixed medium can help us understand the molecular mechanism by which the pathogenresponds to this fungicide. The finding will enhance our understanding of ferimzone's mode of action against fungal pathogens and supprot the development od effective strategies for controlling tea leaf spot disease in the field.