Crystal Structure of SARS CoV-2 Mpro mutant L50F with Nirmatrelvir captured in two conformational states
收藏Protein Data Bank Japan2026-03-04 更新2026-04-11 收录
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Crystal Structure of SARS CoV-2 Mpro mutant L50F with Nirmatrelvir captured in two conformational states Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5, CHLORIDE ION, ... Authors: Shaqra, A.M, Schiffer, C.A. Deposit date: 2022-08-20 Release date: 2024-02-07 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Contributions of Hyperactive Mutations in M pro from SARS-CoV-2 to Drug Resistance. Acs Infect Dis., 10, 2024
创建时间：
2022-08-20
