The frequencies of the most four common haplotypes from rs738992, rs130287, and rs130293 SNPs in HAPE-s and HAPE-r subjects.

Haplotype frequencies were expressed as decimals. A = adenine; C = cytosine; G = guanine; T = thymine; SNPs = single nucleotide polymorphisms; HAPE-s = subjects susceptible to high-altitude pulmonary edema; HAPE-r = subjects resistant to high-altitude pulmonary edema.*The number of haplotype was defined in this study.†Ancestral allele/derived allele according to the NCBI dbSNP database.†P value was calculated by Chi-square test (2×2 contingency table).‡P value was calculated by 2×2 contingency table.§Odds ratio = 0.23 with 95% Confidence Interval from 0.09–0.57.