Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP

NIAID Data Ecosystem2026-05-01 收录

蛋白质调控

分子伴侣功能

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Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP

创建时间：

2023-09-20

Structure-Based Statistical Mechanical Model Accounts for the Causality and Energetics of Allosteric Communication

蛋白质调控

变构药物设计

Allostery is one of the pervasive mechanisms through which proteins in living systems carry out enzymatic activity, cell signaling, and metabolism control. Effective modeling of the protein function r

NIAID Data Ecosystem50

CITE-seq of SUMOi treated C57Bl6 mice

单细胞分析

蛋白质调控

In our study, we investigated the effect of inhibition of SUMOylation on murine splenocytes. Mice were treated with 7,5 mg/kg SUMOi (TAK-981) on day 1 and day 4 and analysed on day5. Single-cell gene

NIAID Data Ecosystem30

Structural Basis for Client Recognition and Activity of Hsp40 Chaperones

蛋白质结构解析

分子伴侣功能

Structural Basis for Client Recognition and Activity of Hsp40 Chaperones Descriptor: Alkaline phosphatase,Chaperone protein DnaJ 2 fusion Authors: Jiang, Y, Rossi, P, Kalodimos, C.G. Deposit date: 201

Protein Data Bank Japan2024-05-15 更新20

Fk1 domain of FKBP51, crystal form III

蛋白质晶体结构解析

分子伴侣功能

Fk1 domain of FKBP51, crystal form III Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP5 Authors: Bracher, A, Kozany, C, Thost, A.-K, Hausch, F. Deposit date: 2010-07-28 Release date: 2011-06-01 L

Protein Data Bank Japan2023-09-06 更新30

High resolution crystal structure of ClpA

蛋白质晶体学

分子伴侣功能

High resolution crystal structure of ClpA Descriptor: ADENOSINE-5'-DIPHOSPHATE, ClpA protein, MAGNESIUM ION Authors: Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L. Deposit date: 2003-10-15 Releas

Protein Data Bank Japan2024-02-14 更新20

Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP

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