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Crystal structure of Thrombin in complex with macrocycle N14-PR4-A

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal structure of Thrombin in complex with macrocycle N14-PR4-A Descriptor: (14S,17R)-14-(3-carbamimidamidopropyl)-3-(furan-2-ylmethyl)-5,12,15-tris(oxidanylidene)-19-thia-3,6,13,16-tetrazatricyclo[19.4.0.0^{6,10}]pentacosa-1(25),7,9,21,23-pentaene-17-carboxamide, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Angelini, A, Kumar, M.G, Heinis, C, Cendron, L. Deposit date: 2019-10-22 Release date: 2020-09-30 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Macrocycle synthesis strategy based on step-wise "adding and reacting" three components enables screening of large combinatorial libraries. Chem Sci, 11, 2020
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2019-10-22
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