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A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation

ChEBI2008-06-11 更新2026-07-21 收录

合成遗传互作网络

组蛋白修饰表观遗传学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-9771 数据链接链接失效反馈

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A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation

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创建时间：

2008-06-11

干细胞衰老

组蛋白修饰表观遗传学

Spermatogonial stem cells (SSC), the foundation of spermatogenesis and male fertility, possess lifelong self-renewal activity. Aging leads to the decline in stem cell function and increased risk of pa

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Gain and loss of H4K16 acetylation during ES cell differentiation [NimbleGen ChIP-chip]. Mus musculus

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H4K16ac is gained on hox loci and lost on pluripotency genes upon differentiation Overall design: ChIP on chip over hox loxi and pluripotency genes for H4K16ac in undifferentiated ES cells and after 3

NIAID Data Ecosystem70

The histone deacetylase SIRT6 controls transcription elongation via promoter- proximal pausing (RNA-Seq)

转录调控

组蛋白修饰表观遗传学

Transcriptional regulation in eukaryotes commonly occurs at promoter-proximal regions wherein transcriptionally engaged RNA Polymerase II (Pol II) pauses before proceeding towards productive elongat

NIAID Data Ecosystem20

Chromatin proteomics reveals novel combinatorial histone modification signatures that mark distinct subpopulations of macrophage enhancers

组蛋白修饰表观遗传学

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The integrated activity of cis-regulatory elements fine-tunes transcriptional programs of mammalian cells by recruiting cell type–specific as well as ubiquitous transcription factors (TFs). Despite th

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Chromatin proteomics reveals novel combinatorial histone modification signatures that mark distinct subpopulations of macrophage enhancers [ChIP-seq]

组蛋白修饰表观遗传学

干细胞增强子功能

The activity of enhancers and promoters fine-tunes the transcriptional program of mammalian cells through the recruitment and interplay between cell type-specific and ubiquitous transcription factors.

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A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation

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