POLYADPRIBOSYL GLYCOHYDROLASE IN COMPLEX WITH PDD00016690
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POLYADPRIBOSYL GLYCOHYDROLASE IN COMPLEX WITH PDD00016690 Descriptor: 1-methyl-~{N}-(1-methylcyclopropyl)-3-[(2-methyl-1,3-thiazol-5-yl)methyl]-2,4-bis(oxidanylidene)quinazoline-6-sulfonamide, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Tucker, J.A, Barkauskaite, E. Deposit date: 2018-09-12 Release date: 2018-11-14 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. J.Med.Chem., 61, 2018
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2018-09-12
