Follicular lymphoma microenvironment characteristics associated with tumor cell mutations and MHC class II expression
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE203610
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资源简介：
Follicular lymphoma (FL) is a B-cell lymphoma with a complex tumor microenvironment that is rich in non-malignant immune cells. We applied single-cell RNA-sequencing to characterize the immune microenvironment of FL. This provides a classification framework of the FL microenvironment, their association with FL genotypes and antigen presentation, and informs different potential immunotherapeutic strategies. scRNA-seq of 20 FL lymph node biopsies and three reactive lymph nodes (RLN) using the 10X Chromium platform to profile the transcriptome in addition to T-cell receptor (TCR) and immunoglobulin (Ig) repertoires. **RAW data has been uploaded to EGA. Accession EGAS00001006052.**
创建时间：
2022-08-28
