GWAS summary statistics for three latent factors of musculoskeletal disorders
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This dataset contains GWAS summary statistics for three latent factors related to musculoskeletal disorders generated using genomic structural equation modeling. The phenotypes are: MSKdh: degenerative musculoskeletal disorder factor MSKbm: bone mass factor MSKai: autoimmune disorder factor The summary statistics include the following columns: SNP: single nucleotide polymorphism (rsID)CHR: chromosomeBP: base pair position based on the GRCh37 reference genomeA1: effect alleleA2: other allele (non-effect allele)EAF: effect allele frequencyBETA: estimated effect size of the effect allele (A1) on the latent factorSE: standard error of the effect size estimateZ: Z statistic (BETA / SE)P: p-value for the association testN: effective sample size Publication: Multivariate genetic analysis reveals three distinct pathological dimensions in musculoskeletal disorders



