FAIRsharing record for: JASPAR

This FAIRsharing record describes: JASPAR is a high-quality, open-access database that provides manually curated, non-redundant transcription factor (TF) binding profiles for six taxonomic groups (fungi, insecta, nematoda, plantae, urochordata, vertebrata). These profiles are stored as position frequency matrices (PFMs), which can be transformed into models to predict TF binding sites (TFBS) in DNA sequences. The database collects motifs both internally, analyzing sequences using a custom motif discovery pipeline, and externally from publications and other resources. All selected motifs are manually curated for quality and supporting evidence. JASPAR now offers a tool for TFBS enrichment analysis in user-provided genomic regions. Data is accessible through the JASPAR website, its RESTful API, Bioconductor, or the Python package pyJASPAR.