Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with a prolylthiazolidine inhibitor #2
收藏Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/3vjl
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with a prolylthiazolidine inhibitor #2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... Authors: Akahoshi, F, Kishida, H, Miyaguchi, I, Yoshida, T, Ishii, S. Deposit date: 2011-10-24 Release date: 2012-10-24 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.393 Å) Cite: Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes Bioorg.Med.Chem., 20, 2012
创建时间：
2011-10-24
