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Synthesis of Isothiocineole and Application in Multigram-Scale Sulfur Ylide Mediated Asymmetric Epoxidation and Aziridination

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DataCite Commons2020-09-20 更新2024-07-13 收录
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http://www.thieme-connect.com/DOI/DOI?10.1055/s-0037-1609580
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资源简介:
The synthesis of the chiral sulfide isothiocineole from limonene and elemental sulfur on multi-gram scale and its alkylation to make >50 g of the corresponding benzylsulfonium salt are described. The application of this salt to the sulfur ylide-mediated asymmetric epoxidation of aldehydes and the asymmetric aziridination of imines on a >5 g scale is demonstrated.
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© Georg Thieme Verlag
创建时间:
2018-07-19
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