DdCBE-mediated mitochondrial base editing in human 3PN embryos
收藏NIAID Data Ecosystem2026-03-13 收录
官方服务:
资源简介:
Sequence Data of Samples
应用场景:
创建时间:
2022-09-01
相关数据集
Direct correction of haemoglobin E / beta-thalassaemia using base editors
Haemoglobin E (HbE)/Ã-thalassaemia causes approximately 50% of all severe thalassaemia worldwide; equating to around 30,000 births per year. HbE/Ã-thalassaemia is due to a point mutation in codon 26
NIAID Data Ecosystem150
基因治疗用载体信息
该数据集包括了基因治疗用的创新设计开发的新型慢病毒载体,该载体与国外已商业化的载体相比具有多方面的优势。该载体信息已专利申请书方式汇交和公开。数据中包括载体的结构信息,位点信息,序列信息,以及结果数据。
国家人口健康科学数据中心80
AAV vector-mediated in vivo miRNA antagonism for studying miRNA function and treating dyslipidemia
Understanding the function of individual miRNA species in mice would require the production of hundreds of loss-of-function strains. To accelerate analysis of miRNA biology in mammals, we combined rec
NIAID Data Ecosystem70
Multiplex viral tropism assay in complex cell populations with single-cell resolution
Gene therapy constitutes one of the most promising mode of disease treatments. Two key properties for therapeutic delivery vectors are the transduction efficiency (how well the vector delivers therape
NIAID Data Ecosystem100
MitoKO: A library of base editors for precise ablation of all protein-coding genes in the mouse mitochondrial genome
We design and apply a highly optimized library of double-stranded DNA deaminase (DddA)-derived cytosine base editors (DdCBEs) - MitoKO - to precisely ablate every mtDNA protein coding gene in the mous
NIAID Data Ecosystem70



