Transcriptome characterization of murine ventricular cardiomyocytes. Mus musculus

We collected comprehensive RNAseq data from wildtype murine ventricular cardiomyocytes. Moreover, a cardiomyocyte-specific knockout mouse model for the ion channel regulator CASK was included, since CASK can translocate to the nucleus and regulate gene expression. Knockout models for SAP97 and dystrophin, two ion channels regulators, were also investigated. Overall design: Sequencing of cardiomycyte RNA from WT mice as well as CASK KO, SAP97 KO and MDX mice. Three replicated experiments were performed for CASK KO and SAP97 KO conditions, and five replicated experiments for the MDX condition.