Human IGF in complex with a Dyrk1B inhibitor
收藏Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4d2r
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Human IGF in complex with a Dyrk1B inhibitor Descriptor: CHLORIDE ION, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR, N-{2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]phenyl}-4-(1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine Authors: Debreczeni, J.E, Kettle, J.G, Ballard, P, Bardelle, C, Butterworth, S, Colclough, N, Critchlow, S.E, Fairley, G, Fillery, S, Graham, M.A, Goodwin, L, Guichard, S, Hudson, K, Mahmood, A, Vincent, J, Ward, R.A, Whittaker, D. Deposit date: 2014-05-12 Release date: 2015-04-22 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery and Optimization of a Novel Series of Dyrk1B Kinase Inhibitors to Explore a Mek Resistance Hypothesis. J.Med.Chem., 58, 2015
创建时间：
2014-05-12
