Effects of H2O2 on SOD1 transgenic flies.

Five day-old male flies expressing SOD1 proteins in motor neurons (A), glial cells (B) and in motoneurons together with glial cells (C) were treated with 1% H2O2 diluted in 3% sucrose. The results indicate an enhancing effect of H2O2 on mutant SOD1 toxiciy in MNs or glia when compared to driver>UAS-dsod1, but not to driver>CS control. Statistical analysis was performed using a two-tailed ANOVA method in Prizm software and was considered significant if p

五日龄的雄性果蝇表达SOD1蛋白于运动神经元（A）、胶质细胞（B）以及与胶质细胞共存的运动神经元（C）中，经1%稀释于3%蔗糖中的H2O2处理。结果显示，与驱动>UAS-dsod1相比，H2O2增强了运动神经元或胶质细胞中突变SOD1的毒性，但并未增强驱动>CS对照组的毒性。统计分析采用Prizm软件中的双尾方差分析（ANOVA）方法进行，若p值小于阈值则认为具有统计学意义。