Microarray analysis of Elavl2 knockout ovaries

Elavl2 knockout female mice show oocyte loss-phenotype shortly after birth. To reveal the involvement of Elavl2 in oogenic gene expression, embryonic and newborn ovaries were subjected to microarray analysis Gene expression analysis using whole ovariesElavl2敲除的雌性小鼠在出生后短期内即呈现卵母细胞缺失表型。为揭示Elavl2在卵发生基因表达中的参与作用，研究人员对胚胎期及新生期卵巢开展了基因芯片（microarray）分析，并采用全卵巢样本进行基因表达检测。