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Crystal structure of a mutant (P393GX) Thyroid Receptor Alpha ligand binding domain designed to model dominant negative human mutations.

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Protein Data Bank Japan2024-01-31 更新2026-04-19 收录
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https://pdbj.org/mine/summary/7qdt
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Crystal structure of a mutant (P393GX) Thyroid Receptor Alpha ligand binding domain designed to model dominant negative human mutations. Descriptor: 3,5,3'TRIIODOTHYRONINE, Isoform Alpha-1 of Thyroid hormone receptor alpha Authors: Romartinez-Alonso, B, Fairall, L, Agostini, M, Chatterjee, K, Schwabe, J. Deposit date: 2021-11-30 Release date: 2022-01-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3 Å) Cite: Structure-Guided Approach to Relieving Transcriptional Repression in Resistance to Thyroid Hormone alpha. Mol.Cell.Biol., 42, 2022
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2021-11-30
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