首页/数据集/Synovial Th17 transdifferentiation into exTh17 sustains chronic IL-17-independent inflammatory arthritis

Synovial Th17 transdifferentiation into exTh17 sustains chronic IL-17-independent inflammatory arthritis

NIAID Data Ecosystem2026-05-10 收录

关节炎免疫病理

Th17细胞

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE234597 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-09-19

Th17细胞

免疫转录组

Th17 cells protect from infections and are pathogenic in autoimmunity. While human Th17 cell differentiation has been defined, the global and stepwise transcriptional changes accompanying this process

NIAID Data Ecosystem80

Reversing SKI–SMAD4-mediated suppression is essential for TH17 cell differentiation

Th17细胞

TGF-β信号通路

Disruption of Ski/Smad4 license Th17 differentiation. TGF-b-Ski-Smad4-RORgt-Th17 axis Examination of transcriptome under two different conditions (WT vs.Smad4 KO), two different treatment (Th0 and IL6

NIAID Data Ecosystem50

Draft genome sequencing of Clostridia bacterium UC5.1-1A9. Clostridia bacterium UC5.1-1A9

基因组测序

Th17细胞

The genome sequences of the 20 Th17-cell-inducing strains were determined by the whole-genome shotgun strategy using an Ion PGM sequencer.

NIAID Data Ecosystem40

SUMOylation of ROR-gt inhibit IL-17 expression and inflamatiion

免疫调控分子

Th17细胞

RNA sequencing of ROR-gt-/- mouse-derived T cells reconstituted with either WT-ROR-gt or mutant (SUMOylation-defective ROR-gt) transcriptomic profiles of 4 WT and 4 mutant mice were analyzed using hig

NIAID Data Ecosystem60

IL-17 Induction by ArtinM is Due to Stimulation of IL-23 and IL-1 Release and/or Interaction with CD3 in CD4+ T Cells

Th17细胞

凝集素-免疫受体互作

ArtinM is a D-mannose-binding lectin extracted from the seeds of Artocarpus heterophyllus that interacts with TLR2 N-glycans and activates antigen-presenting cells (APCs), as manifested by IL-12 produ

Figshare2016-10-31 更新50

Synovial Th17 transdifferentiation into exTh17 sustains chronic IL-17-independent inflammatory arthritis

资源简介：

相关数据集