Androgen deprivation induces double-null prostate cancer via aberrant activation of nuclear export and ribosomal biogenesis by HGF and Wnt axes

NIAID Data Ecosystem2026-05-01 收录

耐药性前列腺癌

肿瘤信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE226556 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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2024-02-26

DataSheet_1_Celastrol Suppresses Glioma Vasculogenic Mimicry Formation and Angiogenesis by Blocking the PI3K/Akt/mTOR Signaling Pathway.pdf

肿瘤信号通路

抗血管生成治疗

Angiogenesis and vasculogenic mimicry (VM) are thought to be the predominant processes ensuring tumor blood supply during the growth and metastasis of glioblastoma (GBM). Celastrol has potential anti-

NIAID Data Ecosystem80

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

肿瘤信号通路

PTEN基因功能

The most recently discovered PTEN tumor suppressor gene has been found to be defective in a large number of human cancers. In addition, germ-line mutations in PTEN result in the dominantly inherited d

PubMed Central1999-04-13 更新60

A somatically acquired enhancer of the androgen receptor is a noncoding driver in advanced prostate cancer. A somatically acquired enhancer of the androgen receptor is a noncoding driver in advanced prostate cancer

耐药性前列腺癌

非编码增强子

Increased androgen receptor (AR) activity drives therapeutic resistance in advanced prostate cancer. The most common resistance mechanism is amplification of this locus presumably targeting the AR gen

NIAID Data Ecosystem40

GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance. GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance

耐药性前列腺癌

雄激素受体信号

Genomic amplification of the androgen receptor (AR) is an established mechanism of antiandrogen resistance in prostate cancer. Here we show that the magnitude of AR signaling output, independent of AR

NIAID Data Ecosystem70

Table_1_Comprehending Meningioma Signaling Cascades Using Multipronged Proteomics Approaches & Targeted Validation of Potential Markers.docx

脑膜瘤蛋白质组学

肿瘤信号通路

Meningiomas are one of the most prevalent primary brain tumors. Our study aims to obtain mechanistic insights of meningioma pathobiology using mass spectrometry-based label-free quantitative proteome

NIAID Data Ecosystem40

Androgen deprivation induces double-null prostate cancer via aberrant activation of nuclear export and ribosomal biogenesis by HGF and Wnt axes

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