Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in covalent complex with TAMRA tagged 1,6-Epi-cylcophellitol aziridine activity based probe
收藏Protein Data Bank Japan2024-11-13 更新2026-03-28 收录
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Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in covalent complex with TAMRA tagged 1,6-Epi-cylcophellitol aziridine activity based probe Descriptor: (1S,2R,3R,4R,5R)-5-[8-[4-(4-azanylbutyl)-1,2,3-triazol-1-yl]octylamino]-4-(hydroxymethyl)cyclohexane-1,2,3-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Sulzenbacher, G, Roig-Zamboni, V, Overkleeft, H, Artola, M. Deposit date: 2023-01-25 Release date: 2023-09-13 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases. Chem Sci, 14, 2023
创建时间：
2023-01-25
