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Rapid emergence of transcriptional heterogeneity upon molecular stress predisposes cells to two distinct states of senescence

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NIAID Data Ecosystem2026-03-14 收录
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We used single-cell RNA-sequencing to characterize different types of senescent cells that arise upon oxidative stress IMR-90 fibroblasts were induced into senescence via oxidative stress. Transcriptional states of individual senescent cells were analyzed via SPLIT-seq method.

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2023-02-03
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