Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179)

NIAID Data Ecosystem2026-05-02 收录

酶催化调控

纳米抗体应用

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Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179)

创建时间：

2024-10-16

Structural basis for the high specificity of a Trypanosoma congolense immunoassay targeting glycosomal aldolase

寄生虫病诊断

纳米抗体应用

Background Animal African trypanosomosis (AAT) is a neglected tropical disease which imposes a heavy burden on the livestock industry in Sub-Saharan Africa. Its causative agents are Trypanosoma parasi

NIAID Data Ecosystem50

Rapid detection and capture of clinical Escherichia coli strains mediated by OmpA-targeting nanobodies. E. coli Nanobodies

病原体检测

纳米抗体应用

Escherichia coli is a major cause of blood stream and urinary tract infections. Owing to the spread of antimicrobial resistance, it is often treated with an inadequate antibiotic. With the aim to acce

NIAID Data Ecosystem20

Nanobodies as novel tools to monitor the mitochondrial fission factor Drp1

细胞分裂机制

纳米抗体应用

In cells, mitochondria undergo constant fusion and fission. An essential factor for fission is the mammalian dynamin-related protein 1 (Drp1). Dysregulation of Drp1 has been linked to neurodegenerativ

NIAID Data Ecosystem00

Antibody RING-Mediated Destruction (ARMeD) of endogenous proteins

靶向蛋白降解

纳米抗体应用

To understand the cellular function of a gene the encoding DNA or mRNA transcript can be manipulated and the consequences observed. However, these approaches do not have a direct effect on the protein

NIAID Data Ecosystem40

Nanobody-aided structure determination of the EPSI:EPSJ pseudopilin heterdimer from Vibrio Vulnificus

蛋白质结构解析

纳米抗体应用

Nanobody-aided structure determination of the EPSI:EPSJ pseudopilin heterdimer from Vibrio Vulnificus

NIAID Data Ecosystem10