POLYADPRIBOSYL GLYCOSIDASE IN COMPLEX WITH PDD00017299
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POLYADPRIBOSYL GLYCOSIDASE IN COMPLEX WITH PDD00017299 Descriptor: 1-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-6-[[(1-methylcyclopropyl)amino]-bis(oxidanyl)-$l^{4}-sulfanyl]-3-[(1-methylpyrazol-4-yl)methyl]quinazoline-2,4-dione, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Tucker, J.A, Barkauskaite, E. Deposit date: 2018-09-12 Release date: 2018-11-14 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. J.Med.Chem., 61, 2018
创建时间：
2018-09-12
