Gene expression data following Neurogenin 1 expression in mouse embryonic stem cells. Mus musculus

To study the early gene expression events involved in neurogenesis, we expressed the bHLH neural determination factor neurogenin 1 in mouse embryonic stem cells. We used microarray to examine the program of gene expression at 24, 48, 72 hours of transgene expression. Overall design: Mouse embryonic stem cells were engineered to express neurogenin 1 using a tet-sensitive expression system. RNAs from uninduced and induced cells were isolated at 24, 48, and 72 hours of differentiation and subjected to microarray analysis.