Calcium-mediated amyloid co-aggregation of S100A1 and S100A8 proteins

NIAID Data Ecosystem2026-05-02 收录

蛋白质聚集机制

钙信号调控

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Supplementary data for "Calcium-mediated amyloid co-aggregation of S100A1 and S100A8 proteins" preprint

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2024-11-25

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Despite the importance of Aβ aggregation in Alzheimer’s disease etiology, our understanding of the sequence determinants of aggregation is sparse and largely derived from in vitro studies. For example

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The proposal involves the study of protein aggregation under volume constraints. Lysozyme as a test protein will dissolved in aqueous conditions within the open cages of a lipid...

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Intracellular pH (pHi) and Ca2+ regulate essentially all aspects of cellular activities. Their inter-relationship has not been mechanistically explored. In this study, we used bases and acetic acid to

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Purkinje neurons with loss of STIM1 exhibit age-dependent changes in gene expression and synaptic components

钙信号调控

神经退行性机制

The Stromal interaction molecule 1 (STIM1) is an ER-Ca2+ sensor and an essential component of ER-Ca2+ store operated Ca2+entry (SOCE). Loss of STIM1 affects metabotropic Glutamate Receptor 1 (mGluR1)

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cAMP-dependent protein kinase involves calcium tolerance through the regulation of Prz1 in Schizosaccharomyces pombe

钙信号调控

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The cAMP-dependent protein kinase Pka1 is known as a regulator of glycogenesis, meiosis, and stress responses in Schizosaccharomyces pombe . We demonstrated that Pka1 is responsible for calcium

Taylor & Francis Group2017-01-13 更新40

Calcium-mediated amyloid co-aggregation of S100A1 and S100A8 proteins

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