Table displays significant associations of eQTL genes and metabolites for validated loci. Genes and metabolites are ordered according to strength of association. Statistics of strongest associations a
One-carbon metabolism (OCM) is linked to DNA synthesis and methylation, amino acid metabolism and cell proliferation. OCM dysfunction has been associated with increased risk for various diseases, incl
BackgroundThere is very limited evidence on the causal effects of blood metabolites on pancreatitis risks. To reveal the causal associations between plasma metabolites and pancreatitis risks, we perfo
a SNP with the strongest association to targeted metabolic traits (“lead SNP”) b SNP with the strongest association to non-targeted metabolic traits c manually added to the list of most plausible cand
Significant results are highlighed above inbold.Note: rs1799941 was coded dominantly for the effect of the minor allele (homozygous major = 0, heterozygote = 1, homozygous minor = 1). Odds ratios pres
