CETSA with YLIU-06-026-1 on P. falciparum

NIAID Data Ecosystem2026-05-02 收录

抗疟药物靶点

热位移分析

数据链接：

https://www.omicsdi.org/dataset/pride/PXD053974 数据链接链接失效反馈

官方服务：

资源简介：

ITDR MS-CETSA was conducted with YLIU-06-026-1 on P. falciparum lysates and live parasite culture in trophozoite stage.

创建时间：

2025-06-16

Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound

疟原虫酶结构

抗疟药物靶点

Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound Descriptor: 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl py

Protein Data Bank Japan2023-12-27 更新90

Plasmodium vivax N-myristoyltransferase in complex with YnC12-CoA thioester.

疟原虫酶结构解析

抗疟药物靶点

Plasmodium vivax N-myristoyltransferase in complex with YnC12-CoA thioester. Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, ... Authors: Wright, M.H, Clough, B

Protein Data Bank Japan2024-05-08 更新20

Potent acyl CoA synthetase 10 inhibitors disrupt triglyceride formation in P. falciparum. undefined

疟原虫代谢

抗疟药物靶点

Identifying how small molecules that kill malaria parasites work can lead to new, “chemically validated” targets. Selections with three novel structurally-unrelated compounds (MMV665924, MMV019719 and

NIAID Data Ecosystem10

Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery

抗疟药物靶点

进化基因组学靶标验证

Although many new anti-infectives have been discovered and developed solely using phenotypic cellular screening and assay optimization, most researchers recognize that structure-guided drug design is

NIAID Data Ecosystem40

Upregulated proteins in ICL-M-treated P . falciparum 3D7.

疟原虫蛋白质组学

抗疟药物靶点

Upregulated proteins in ICL-M-treated P. falciparum 3D7.

NIAID Data Ecosystem20