Co-Crystal Structure of MDM2 with Inhbitor Compound 46
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Co-Crystal Structure of MDM2 with Inhbitor Compound 46 Descriptor: 6-{[(2R,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-2-methyl-3-oxomorpholin-2-yl]methyl}pyridine-3-carboxylic acid, E3 ubiquitin-protein ligase Mdm2, SULFATE ION Authors: Shaffer, P.L, Huang, X, Yakowec, P, Long, A.M. Deposit date: 2014-01-16 Release date: 2014-04-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5361 Å) Cite: Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres. J.Med.Chem., 57, 2014
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2014-01-16
