Catalyst and Solvent Free Domino Ring Opening Cyclization: A Greener and Atom Economic Route to 2‑Iminothiazolidines
收藏NIAID Data Ecosystem2026-03-10 收录
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A catalyst-free regioselective synthesis of 2-iminothiazolidines has been achieved by reacting unactivated aziridines with aroyl isothiocyanates at ambient temperature in 100% atom economy via a domino ring opening cyclization. The present protocol operates under solvent free conditions as well as in the absence of any catalyst making it a greener and ecofriendly approach.
创建时间:
2018-02-14



