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CryoEM Structure of HCA2-Gi1 in complex with MK-1903

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Protein Data Bank Japan2025-05-14 更新2026-04-25 收录
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CryoEM Structure of HCA2-Gi1 in complex with MK-1903 Descriptor: (4aR,5aR)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Krumm, B.E, Kang, H.J, Diberto, J.F, Kapolka, N.J, Gumpper, R.H, Olsen, R.H.J, Huang, X.P, Zhang, S, Fay, J.F, Roth, B.L. Deposit date: 2023-10-30 Release date: 2025-02-26 Last modified: 2025-05-14 Method: ELECTRON MICROSCOPY (3.24 Å) Cite: Structure-guided design of a peripherally restricted chemogenetic system. Cell, 187, 2024
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2023-10-30
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