Crystal structure of human DHODH in complex with inhibitor 0944
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Crystal structure of human DHODH in complex with inhibitor 0944 Descriptor: 3-[3,5-bis(fluoranyl)-4-(3-methoxyphenyl)phenyl]benzo[f]benzotriazole-4,9-dione, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... Authors: Chen, Q, Yu, Y. Deposit date: 2020-01-09 Release date: 2020-09-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.802 Å) Cite: Bifunctional Naphtho[2,3- d ][1,2,3]triazole-4,9-dione Compounds Exhibit Antitumor Effects In Vitro and In Vivo by Inhibiting Dihydroorotate Dehydrogenase and Inducing Reactive Oxygen Species Production. J.Med.Chem., 63, 2020
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2020-01-09
