官方服务:
资源简介:
Effects of engineered Treg GI-homing cells (GPR15 Treg) on the intestinal microbiota for the treatment of acute graft-versus-host-disease (aGVHD).
应用场景:
创建时间:
2024-08-30
相关数据集
Early life microbiota exposure restricts myeloid-derived suppressor cell driven colonic tumorigenesis
Gut microbiota and their metabolites are instrumental in regulating homeostasis at intestinal and extra-intestinal sites. However, the complex effects of prenatal and early postnatal microbial exposur
NIAID Data Ecosystem80
Targeting Interleukin-2-Inducible T-cell Kinase (ITK) differentiates GVL and GVHD in allo-HSCT
Allogeneic hematopoietic stem cell transplantation is a potentially curative procedure for many malignant diseases. Donor T cells prevent disease recurrence via graft-versus-leukemia (GVL) effect. D
NIAID Data Ecosystem50
Table_7_Safety and Efficacy of Fecal Microbiota Transplantation for Grade IV Steroid Refractory GI-GvHD Patients: Interim Results From FMT2017002 Trial.docx
Gastrointestinal (GI) tract graft-versus-host disease (GvHD) is a major cause of post-allo-HSCT (hematopoietic stem cell transplantation) morbidity and mortality. Patients with steroid-refractory GI-G
NIAID Data Ecosystem10
D-amino acids control IgA production
Intestinal microbiota produces D-amino acids, which are bacteria-specific metabolites, for their growth and their communication. Host intestine release D-amino acid oxidase (DAO) to degrade bacterial
NIAID Data Ecosystem60
Ambient oxygen levels regulate intestinal dysbiosis and GVHD severity after allogeneic stem cell transplantation
T-cell mediated gastro-intestinal (GI) diseases such as graft-versus-host host disease (GVHD) and inflammatory bowel diseases (IBD) cause significant morbidity and mortality. Multiple studies have cor
NIAID Data Ecosystem20



