When challenged with an invading pathogen, host defense mechanisms are engaged to eliminate the pathogen (resistance) and limit tissue damage that results from host-pathogen interactions (disease tole
Transcription profiling by array of human blood monocyte stimulated with various stimuli (control, MRP8, LPS, TNF, IL1) to study signalling pathways in phagocytic activation
P2X7 is a ligand-gated ion channel which is activated by ATP and displays secondary permeability characteristics. The mechanism of development of the secondary permeability pathway is currently unclea
Raw imaging data that was used to generate the main figure 6 for Akama-Garren et al. 2023 "Regulation of immunological tolerance by the p53-inhibitor iASPP". Please refer to the paper in Cell Death &
