Dataset for 'Identification of immunodominant T cell epitopes in SARS-CoV-2 spike protein in Syrian hamsters'

This dataset contains all raw data underlying the main and supplementary figures of the manuscript “Identification of Immunodominant T Cell Epitopes in the SARS-CoV-2 Spike Protein in Syrian Hamsters” published in The Journal of Immunology. It includes measurements of T cell responses in Syrian hamsters immunized with a replication-defective ChAd-SARS-CoV-2-S vaccine encoding a pre-fusion–stabilized Wuhan-1 spike protein. The dataset also provides comparative T cell–response data following in vivo CD4 or CD8 depletion. In addition, it identifies key CD4 and CD8 epitopes within the most immunogenic regions of the spike protein.