Fitness effects of inherited STR alleles.

For each individual tested, the table shows the number of variant STR alleles, number of STR alleles considered, total additive burden, and mean s per variant allele (see Methods). STRs from classes with poor model fits (KS score ≤ 50, see S2 Table) were excluded. We also present scaled burdens and mean allele effects that divide the original values by 2 to be comparable to SNV-based burden calculations (see Methods). (XLSX)