five

ERK signalling orchestrates neural differentiation by promoting the polycomb repressive complex [dataset 1]

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https://www.ncbi.nlm.nih.gov/sra/SRP165211
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资源简介:
In this experiment patterns of chromatin accessibility were compared in (H9) human ES cell derived neuromesodermal progenitors (NMP-L)s and derived neural progenitors (NP)s at different days during the neural differentiation procedure (day 5, day 6 and day 8) and also in NPs at day 5 and 6 exposed to carrier control with DMSO or the MEK inhibitor PD184352. Overall design: In this experiment we compared chromatin accessibility in NMP-Ls, NPs day 5, day 6 and day 8 as well as in NPs day 5 and 6 with DMSO or MEK inhibtor treatment. Experiments wer done in biological duplicates. With untreated and DMSO treated cells fuctioning as the controls for MEK inhibitor treated cells.
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2022-12-17
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