Lactiplantibacillus plantarum PMO08 Genome sequencing and assembly

Lactiplantibacillus plantarum PMO08 has been developed as cholesterol-lowering probiotic and used as a probiotic starter in Pulmuone Co., Ltd. [1]. This strain was isolated from kimchi, a Korean fermented vegetable, with high stability under gastrointestinal conditions [2]. In addition, several studies reported its health-promoting activities such as anti-inflammatory in vitro [3], cholesterol-lowering in mice [4], and gut microbiome shaping in human [5]. [References] 1.Oh YJ, Kim TS, Moon HW, Lee SY, Lee SY, Ji GE, et al. Lactobacillus plantarum PMO 08 as a Probiotic starter culture for plant-based fermented beverages. Molecules. 2020;25(21):5056. 2.Jang SE, Hyun YJ, Trinh HT, Han MJ, Kim DH. Anti-scratching behavioral effect of Lactobacillus plantarum PM008 isolated from kimchi in mice. Immunopharmacol Immunotoxicol. 2011;33(3):539-44. 3.Jang SE, Hyun YJ, Oh YJ, Choi KB, Kim T, Yeo IH, et al. Adhesion activity of Lactobacillus plantarum PM 008 isolated from kimchi on the intestine of mice. J Bacteriol Virol. 2011;41(2):83-90. 4.Oh YJ, Kim HJ, Kim TS, Yeo IH, Ji GE. Effects of Lactobacillus plantarum PMO 08 alone and combined with chia seeds on metabolic syndrome and parameters related to gut health in high-fat diet-induced obese mice. J Med Food. 2019;22(12):1199-207. 5.Oh YJ, Nam K, Kim Y, Lee SY, Kim HS, Kang JI, et al. Effect of a nutritionally balanced diet comprising whole grains and vegetables alone or in combination with probiotic supplementation on the gut microbiota. Prev Nutr Food Sci. 2021;26(2):121. [Patents] 1. Lactobacillus plantarum PMO08 having anticancer or antibacterial activity and method for preparing fermented product by lactic acid bacteria using vegetable ingredients 2. Composition for preventing, treating or improving gastrointestinal disease comprising plant originated lactic acid bacteria, Lactobacillus plantarum PMO08 as an active ingredient