Supplemental material, sj-sas-7-smm-10.1177_09622802211051089 for Allowing for stratification in sample size planning of two-arm trials with continuous or binary outcome: Overview and tutorial by Stef
In this article, we consider randomized trial design to evaluate interventions with spatially or spatio-temporally heterogeneous effects. A common approach in this setting is the cluster randomized tr
Adaptive two-stage design with treatment selection, also called seamless Phase II/III design, has been recognized to save sample size and time to enhance the development of effective treatments. These