Mean concentration of fasting glucose, insulin and HOMA-IR scores in antipsychotic drug treated rats.

I0 = fasting insulin levels (µU/ml); G0 = fasting glucose levels (mmol/L); HOMA-IR = homeostasis model assessment of insulin resistance (µU·mmol)/(ml·L). Rats were treated with three separate doses of lurasidone (0.2, 0.8 or 2.0 mg/kg), olanzapine (10 mg/kg) or vehicle. Values represented as means ± SEM at t = 30 min during the IGTT. *indicates different from vehicle-treated animals, p<0.001. Mean concentration of fasting glucose, insulin and HOMA-IR scores in antipsychotic drug treated rats.