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Gene expression data from SKOV3 cell line with SND1 knockdown

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE115784
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SND1 protein is a highly conserved protein of eukaryotic cells and is involved in a group of cellular biological processes, such as gene transcription, pre-mRNA splicing, cell cycle, DNA damage repair, proliferation and programmed cell death degradome, adipogenesis and cancerogenesis. SND1 can promote the metastasis and proliferation of breast cancer cells by down-regulating the miR-127 expression. Herein, we used microarrays to detail the potential molecular mechanism in the ovarian cancer tumorigenesis. Total RNA were extracted in SKOV3 cells transfection with shSND1 and pLKO-Vector respectively. cDNA was synthesized and hybridised to Affymetrix microarrays.
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2021-06-14
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