Highly optimized CNS penetrant inhibitors of EGFR Exon20 Insertion Mutations
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Highly optimized CNS penetrant inhibitors of EGFR Exon20 Insertion Mutations Descriptor: 1-[2-[5-(1,3-benzoxazol-4-yl)-2,4-bis(fluoranyl)phenyl]-3-pyrimidin-4-yl-4,6-dihydropyrrolo[3,4-d]imidazol-5-yl]propan-1-one, Epidermal growth factor receptor, SULFATE ION Authors: Hargreaves, D. Deposit date: 2024-08-01 Release date: 2025-02-12 Last modified: 2025-02-26 Method: X-RAY DIFFRACTION (1.909 Å) Cite: Highly Optimized CNS Penetrant Inhibitors of EGFR Exon20 Insertion Mutations. J.Med.Chem., 68, 2025
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2024-08-01
