Crystal Structure of the first bromodomain of human BRD4 BD1 in complex with the inhibitor Y13195
收藏Protein Data Bank Japan2024-12-25 更新2026-06-30 收录
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Crystal Structure of the first bromodomain of human BRD4 BD1 in complex with the inhibitor Y13195 Descriptor: 7-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-5-methyl-2-(2-phenyl-1H-imidazol-5-yl)furo[3,2-c]pyridin-4(5H)-one, BRD4_HUMAN, DIMETHYL SULFOXIDE, ... Authors: Li, J, Hu, Q, Xu, H, Zhao, X, Zhang, C, Zhu, R, Wu, X, Zhang, Y, Xu, Y. Deposit date: 2024-05-22 Release date: 2024-12-11 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Discovery of the First BRD4 Second Bromodomain (BD2)-Selective Inhibitors. J.Med.Chem., 67, 2024
创建时间：
2024-05-22
