SNPs meeting p<10–3 significance threshold for potential locus-smoking interaction for incident T2D in discovery stage analyses among EA individuals and AA individuals.
BackgroundFat mass and obesity (FTO) and melanocortin-4 receptor (MC4R) and are relevant genes associated with obesity. This could be through food intake, but results are contradictory. Modulation by
Genome wide association studies (GWAS) identified a chromosome 8 locus associated with fasting glucose (FG), insulin (FI) and lipid levels that is located near PPP1R3B (a gene which encodes the cataly
Additional file 6. Table S5. Results of Interaction Tests for the Effects of Age, Sex and Body Mass Index on Associations between Candidate Variants and Obstructive Sleep Apnoea Diagnosis.
The association between rs73449607 or rs79967607 and type 2 diabetes in the Population Architecture Genomics and Epidemiology/DIAbetes Genetics Replication and Meta-analysis (PAGE/DIAGRAM) study.
* Year of birth: 1900–1960. #The denominator for calculating the relative risk is the prevalence in the total population born in the same time period. The prevalence for the total population is 0.046