Actn4

ENCODES a protein that exhibits protein-containing complex binding; structural constituent of postsynaptic actin cytoskeleton; ubiquitin protein ligase binding; INVOLVED IN regulation of apoptotic process; response to hypoxia; actin filament bundle assembly (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; Entamoebiasis pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN glutamatergic synapse; neuron projection; postsynaptic actin cytoskeleton; INTERACTS WITH 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene

编码一种表现出蛋白质复合物结合特性的蛋白质；突触后肌动蛋白细胞骨架的结构成分；泛素蛋白连接酶的结合；参与凋亡过程的调控；对缺氧的反应；肌动蛋白束组装（同源）；参与血小板源生长因子信号通路；心律失常性右心室心肌病通路；溶组织阿米巴病通路；与动物乳腺肿瘤（同源）相关；癌（同源）；化学和药物诱导的肝损伤（同源）；存在于谷氨酸能突触；神经元投射；突触后肌动蛋白细胞骨架；与2,2,2-四氨基；2,3,7,8-四氯二苯并-对二恶英；2,6-二硝基甲苯相互作用。