Colorectal adenoma recurrence: an analysis of gut microbiota characteristics

Colorectal adenoma (CRA) is precancerous lesion of colorectal cancer (CRC). Early detection and endoscopic resection of CRA are the most effective methods for preventing CRC, yet there is a significant recurrence risk. We aim to explore the gut microbiota characteristics in individuals with recurrent CRA, in order to provide new insights for risk stratification and intervention. We recruited 30 participants with recurrent CRA and 15 participants without CRA recurrence. Fecal samples were collected from all participants and 16s rRNA sequencing was performed to analyze the composition, structure, and functional gene differences of the gut microbiota.