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The Scc2NIPBL/Scc4MAU2 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions [microarray]

Alliance of Genome Resources2026-08-01 收录

姐妹染色单体凝聚

核小体游离区域调控

数据链接：

https://www.yeastgenome.org/dataset/GSE56991 数据链接链接失效反馈

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资源简介：

The Scc2/Scc4 complex binds to broad nucleosome-free regions in the promoters of highly expressed genes

应用场景：

姐妹染色单体凝聚

DNA损伤响应

It is widely accepted that of the four Replication Factor C (RFC) complexes (defined by the associations of either Rfc1p, Ctf18p, Elg1p or Rad24p with Rfc2p-Rfc5p), only Ctf18-RFC functions in sister

NIAID Data Ecosystem70

Microarray analysis comparing yeast Eco1 mutant W216G to mutants of FOB1 and RAD61

裂殖酵母基因表达

姐妹染色单体凝聚

Eco1 is an acetyltransferase subunit of the cohesin complex and acts during DNA replication to establish cohesion between sister chromatids. However, cohesin has additional functions in gene expressio

NIAID Data Ecosystem30

Models for cohesion and cohesion-mediated chromosome segregation.

姐妹染色单体凝聚

染色体分离机制

(A) SeqA-dependent precatenane removal. Positive supercoils migrate behind the replisome, entwining newly replicated sister regions. Resolution of precatenanes by Topo IV (green) is delayed by SeqA (r

NIAID Data Ecosystem20

A long noncoding RNA regulates sister chromatid cohesion [microarray]. Homo sapiens

非编码RNA功能

姐妹染色单体凝聚

Long noncoding RNAs (lncRNAs) have appeared to be involved in the most diverse cellular processes through multiple mechanisms. Here we describe a previously uncharacterized human lncRNA, CONCR (cohesi

NIAID Data Ecosystem30

MCM2-7-dependent cohesin loading during S phase promotes sister-chromatid cohesion

染色质免疫沉淀测序

姐妹染色单体凝聚

We employ ChIP-seq methodology to study genome-wide distribution of MCM2, NIPBL and cohesin in thymidine-arrested cells Antibodies against MCM2, RAD21 or NIPBL were used to detect MCM2, RAD21 or NIPBL

NIAID Data Ecosystem30

The Scc2NIPBL/Scc4MAU2 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions [microarray]

资源简介：

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