Transcriptional profiling of yellow fever vaccine-naive participants bafore and after vaccination against yellow fever.

Mechanisms of poor responses to vaccines remain unknown. Yellow fever-naive adults were vaccinated with a yellow fever vaccine (YF-17D, Stamaril). Transcriptomic profiling of blood collected pre-vaccination and post-vaccination (day 3, 7, 14 and 84) was performed in order to identify candidate biomarkers of antibody response to the vaccine.