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Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 7

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 7 Descriptor: N-(4-bromo-3-methylbenzoyl)-4-[difluoro(phosphono)methyl]-L-phenylalanyl-N~5~-(3-iodobenzoyl)-L-ornithyl-3-{[(4-hydroxy-3-methoxyphenyl)acetyl]amino}-D-alaninamide, Tyrosine-protein phosphatase non-receptor type 9 Authors: Zhang, Z.-Y, Liu, S, Zhang, S. Deposit date: 2012-08-01 Release date: 2012-10-31 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes. J.Am.Chem.Soc., 134, 2012

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2012-08-01
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