mGlur2 with glutamate analog
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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mGlur2 with glutamate analog Descriptor: (1R,2S,4R,5R,6R)-2-amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2 Authors: Monn, J.A, Clawson, D.K. Deposit date: 2015-07-17 Release date: 2015-09-09 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist. J.Med.Chem., 58, 2015
创建时间：
2015-07-17
